Metastatic cerebellar tumor from esophageal squamous carcinoma: a case report and review of the literature
DOI: 10.54647/cm32699 79 Downloads 5135 Views
Author(s)
Abstract
Esophageal cancer is one of the most fatal malignancies. It is often diagnosed during its advanced stages. Brain metastases, and especially cerebellar ones have been infrequently reported in the Literature. In patients with large cerebellar metastases, surgical removal is still the most effective therapy for improving survival and Karnofsky Performance Score (KFS). Stereotactic Radiosurgery is another treatment option for multiple brain metastases but the improvement in survival was only demonstrated in single metastasis. We report a case of multiple cerebellar metastases from esophageal squamous cell cancer in a 64 years old male, who underwent macroscopic total resection of all lesions.
Up to date no treatment guidelines exist for esophageal cancer brain metastases. Multimodal therapy including surgery, radiation, and chemotherapy is now generally recommended for treatment of these lesions. Total resection of cerebellar ones should be the aim of surgical therapy, especially if a good KPS is expected.
Keywords
Brain Metastases; Carcinoma; Craniotomy; Total resection; Radiotherapy; Chemotherapy
Cite this paper
Ludovica Cellini, Gonçalo Januário, Gonçalo Novais,
Metastatic cerebellar tumor from esophageal squamous carcinoma: a case report and review of the literature
, SCIREA Journal of Clinical Medicine.
Volume 7, Issue 2, April 2022 | PP. 86-93.
10.54647/cm32699
References
[ 1 ] | Epidemiology of esophageal cancer. Yuwei Zhang. World J Gastroenterol. 2013 Sep 14. |
[ 2 ] | Esophageal Cancer: Risk Factors, Genetic Association, and Treatment. Fang-Liang Huang et al. Asian J Surg. May 2018. |
[ 3 ] | Esophageal Cancer. Benjamin R. Alsop et al. Gastroenterol Clin North Am. Sep 2016. |
[ 4 ] | Esophageal Cancer Metastases to Unexpected Sites: A Systematic Review. Osama Shaheen et al. Gastroenterol Res Pract. 2017. |
[ 5 ] | Surgical treatment of cerebellar metastases. Ali J. Ghods et al. Surg Neurol Int. 2011. |
[ 6 ] | Retrospective Study of 127 Surgically Treated Patients With Multiple Brain Metastases: Indication, Prognostic Factors, and Outcome. Gabriele Schackert et al. Acta Neurochir (Wien). Mar 2013. |
[ 7 ] | Brain Metastases from Esophageal Carcinoma: Natural History, Prognostic Factors, and Outcome. Ogawa K. Et al. Cancer. 2002. |
[ 8 ] | Results and prognostic factors in a consecutive series of 44 operated patients.Pompili A. et al. J Neurooncol. 2008. |
[ 9 ] | Diagnosis and treatment of brain metastases from solid tumors: guidelines from the European Association of Neuro-Oncology (EANO). Riccardo Soffietti et al. Neuro-Oncology. 2017. |